Ichthyosis (Jack Russell Terrier Type)

General Information: Ichthyosis (Jack Russell Terrier Type) is a hereditary skin condition that affects dogs, characterized by widespread scaling that resembles parchment, particularly noticeable on non-haired or lightly haired areas such as the abdomen. This condition is present from birth and often persists into adulthood, leading to potential secondary infections, including ear infections. Affected dogs may also experience skin overgrowth on the foot pads and soft nails. Unlike some other skin conditions, ichthyosis typically does not cause hair loss. Management of ichthyosis focuses on improving skin health and preventing complications through the use of topical and oral medications, which can help alleviate symptoms and maintain the quality of life for affected dogs.

How to Read Your Dog's Test Results for this Genetic Variant:

Two Variants Detected: Dog Likely Affected

One Variant Detected: Dog Unlikely Affected

No Variants Detected: No Effect

Gene / Testing Information: Genetic testing for the TGM1 gene is essential to identify carriers of the mutation responsible for Ichthyosis (Jack Russell Terrier Type). This condition is inherited in an autosomal recessive manner, meaning a dog must inherit two copies of the mutated gene, one from each parent, to develop the disease. Dogs carrying only one copy of the mutation (carriers) do not show symptoms but can pass the gene to their offspring. When two carriers are bred, each puppy has a 25% chance of developing ichthyosis and a 50% chance of being a carrier. Reliable genetic testing is crucial for responsible breeding practices to avoid mating two carriers, thereby reducing the risk of producing affected puppies. By ensuring that only non-carrier dogs are bred, breeders can help eliminate this mutation from the Jack Russell Terrier population, promoting healthier and more resilient future generations.