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White Spotting (S Locus) Parti or Piebald

The S Locus (S) (White Spotting) genetic variation, associated with the MLPH gene, influences coat color dilution in dogs, leading to phenotypes like blue, charcoal, and lilac.

Affected Genes: MITF

Variant(canFam6):
chr20:21860725: 199 bp insertion

Breed: All

References:
Karlsson EK, Baranowska I, Wade CM, Salmon Hillbertz NH, Zody MC, Anderson N, Biagi TM, Patterson N, Pielberg GR, Kulbokas EJ 3rd, Comstock KE, Keller ET, Mesirov JP, von Euler H, Kampe O, Hedhammar A, Lander ES, Andersson G, Andersson L, Londblad-Toh K. Efficient mapping of mendelian traits in dogs through genome-wide association. Nat Genet. 2007 39(11):1321-1328.